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Medical Channel Journal
2022, Volume 18, Issue 1 : 63-65
Research Article
Serum calcium level and pregnancy induced hypertension
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Gynae and Obstetric Unit-II, Dow Medical Sciences and College, Civil Hospital Karachi and Dow University Health and Sciences, Pakistan
Abstract

Pregnancy induced hypertension (PIH) is one of the major causes of maternal and most studied conditions associated with PIH which may be reduced by calcium supplementation. Objective: To compare mean serum calcium level among normotensive and pregnancy induced hypertensive women presenting in tertiary care hospital. Methods: The study was carried out in outpatient department of Gynae and Obstetrics from Feb to August 2010. It was a case control study and 30 PIH patients between 15-40 years and 30-42 weeks gestation with singleton fetus were enrolled as cases and 30 normotensive women with similar age and gestation age were included as controls. Both groups were given calcium supplementations in same dosage. Pregnant women with essential hypertension, renal disease, heart disease, UTI and diabetes were excluded. Blood sample of 3cc was collected for serum calcium level. Aga, gestational age, serum calcium level, educational status and monthly income was noted in the proforma. Data analysis was done by SPSS-15. Mean and SD was calculated for age, gestational age and serum calcium level. Frequency of educational status and monthly income was calculated by Chi-Square tests. Unpaired t-test was applied to compare mean serum calcium level between two groups. Relationship of calcium level with gestational age was estimated by logistic regression. Results: There was no significant difference in the mean age and gestational age of both groups. But significantly low serum calcium level found in PIH group as compared to control group (7.91±0.935 vs 9.09±0.837 mg/dl). Gestational age 38 to 40 weeks had approximately 3 times greater risk of hypocalcemia (OR = 2.62) as compared to gestational age 34 to 37 weeks. Conclusion: Significantly low level of serum calcium was found in women with PIH verses normotensive women, thus supporting the association of serum calcium level with this disorder of pregnancy.

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