Objective: To assess the knowledge, attitude and practices pertaining to breast feeding in general community and to find out the factors associated with failure to breast feed. Place and Duration of Study: The study was carried out at Civil Hospital Karachi from July 2008 to June 2009. Patients and Methods: Two hundred women's along their infants up to 6 months of age were enrolled in the study. These patients reported to the hospital for routine post partum check-ups or vaccinations. A questionnaire was designed in conjunction with critical ideas about breast feeding, pattern and the reasons for not continuing breast feeding up to the age of 6 month. Results: 42.5% of the women knew the general benefits of breast feeding and the dangers of bottle-feeding. Believes and perceptions hampered exclusive breast feeding practices. Gender-biased behavior was also found in the study; 66.6% of the male babies while 40% of the female babies 40 % were breast fed. Inadequate milk production was the most common reason (55%); maternal employment was seen in 10%, maternal systematic illness was found in 13.5%. Current pregnancy that is succeeding pregnancy in 10% was associated with breast feeding failure. Conclusion: It is concluded that breast feeding, besides its nutritional and health advantages, is vital for better infant and mother relationship. Ignorance is an important factor; likewise nutritional education should be given to eradicate malnutrition in infants.