Introduction: Peripheral nerves are injured commonly by mechanical trauma, the terms applied to the timing of the nerve repair include primary repair (immediately after injury, or within 6 to 12 hours), delayed primary repair (usually within the first 2 to 2.5 weeks), and secondary repair (after 2.5 to 3 weeks). This study was conducted to analyze the clinical outcome of median and ulnar nerve repair at wrist.

Material and Method : This Prospective observational study was conducted at Liaquat University of medical & Health Sciences, Jamshoro.Twenty five patients, (37 nerves), with age range between 25 to 50 years, were included in the study and followed on average 24 months. Common cause of injury was sharp laceration as result of knife injury or sharp glass injury. Delayed primary repair(epineurialneurorrhaphy) was performed in all patients. The associated injuries to tendons were dealt at the same time. Informed consent was taken from all patients before their inclusion in study.

Results: The results of unlar nerve repair: motor function recovery was fair in 8/19, (42.10%) nerves and good in 4/19(21.05%), and unsuccessful in 7/19 (36.8%) nerves. The sensory recovery was fair in 5/19 (26.31%) nerves and good in 7/19 (36.84%) nerves and unsuccessful in 7/19 (36.8%) repaired nerves.

The results of Median Nerve repair: Motor function recovery was fair in 6/18(33.33%) and good in 4/18 (22.22%), and unsuccessful in 8/18 (44.44%) repaired median nerves. The sensory recovery was fair in 4/18 (22.22%) and good in 6/18 (33.33%), and unsuccessful in 8/18 (44.44%) repaired median nerves. Post operative wound infection was seen in 7/25 patients (28%). The infection was treated with drainage debridement and appropriate antibiotics.

Conclusion: The results of median and ulnar nerve delayed primary repair may be adverselyaffected by infection, use of thick thread, and operating without magnification.