Objective of Study: To look for malarial parasite and its species in hospitalized children, who were clinically suspected as malaria. Background: Malaria is the most devastating disease in world. Over three billion people live under the threat of malaria in 24 endemic countries and it kills over a million each year, majority being children. Study Design: Descriptive. Materials & Methods: This is hospital based retrospective study conducted at Children hospital Chandka Medical College Larkana from Jan 2008 to Dec 2008. Files of patients who were clinically diagnosed as malaria according to World Health Organization/ National Malaria Program were reviewed. Data regarding age, sex and malarial parasites and their species was collected. Data was analyzed by using SPSS version 15 for windows and results were presented as frequency tables, Charts and Graphs. Results: Two patients were clinically suspected as malaria. Majority of patients 139(69.5%) were between five to twelve years. There was male predominance 117(58.5%). Malaria parasites were seen in 73(36.5%), Plasmodium, Falciparum was seen in majority 43(58.9%) of cases, Vivax was seen in 30(41.09%), there was no case of plasmodium malairae or plasmodium ovale. Majority of patients 196(98%) improved and were discharged, 04(2%) patients died Conclusion: Out of 200 clinically suspected cases of malaria, 73(36.5%) were malarial parasite positive, Plasmodium falciparum was predominant specie.