Objective: To assess the results of fine needle aspiration as an adjunct tool for breast lump evaluation in terms of sensitivity, specificity and diagnostic validity. Methodology: Study design: Prospective analytical study. Study setting: Department of Surgery, Liaquat University of Medical & Health Sciences, Jamshoro. Sample size: Ninety five patients Sample technique: Non-probability convenient sampling technique after obtaining informed consent. Study duration: February 2007 to January 2009. Results: A total of 95 females, 86 (90.52%) married and 9 (9.47%) unmarried were included in the study. Mean age of our patient was 38 years (range 14-70 years). All patients (100%) were presented with the history of breast lump of duration about 4 months to more than 2 1/2 years. Out of 95 patients, 83(87.3%) had unilateral lump and 12 (12.7%) had bilateral lump. Forty six (48.2%) gave history of breast pain while 66 (69.4%) had history of weight loss. Comparison of FNAC and histopathology results done, for 29 malignant lesions FNAC could detect 21 (72.4%) and 4 (13.7%) were graded as suspicious of malignancy and 4 (13.7%) were remained undiagnosed. Due to thorough conservative approach there was no false positive diagnosis. For 66 benign lesions on histopathology, FNAC could diagnose 54 (81.8%) and 12 (18.18%) labeled unsatisfactory for diagnosis. Analysis of cytology reports showed that there were 21(72.4%) true positive (TP) for malignancy and 4 (6.06%) were false negative (FN), 54 (81.81%) were true negative (TN) for malignancy and there was no false positive. Conclusion: Mastectomies can be prevented by early diagnosis and open biopsies need can be reduced. FNAC should be routinely used as a part of clinical sequence to determine the nature of breast lump.